Personalized cardiopulmonary resuscitation device for emergency teams, Enhancement of an advanced clinical trial recruitment platform for Europe to ensure maximum intake of eligible consenting patients for participation, Metrology of Carbohydrates for Enabling European Bioindustries, ZIKAction: Preparedness, research and action network on maternal-paediatric axis of ZIKV infection in Latin America and the Caribbean, Defining functional networks of genetic causes for ALS and related neurodegenerative disorders, THE ROLE OF MUCINS AND MUCUS IN THE DISEASES CYSTIC FIBROSIS, CELIAC DISEASE, AND ULCERATIVE COLITIS, Precision Multi-Spectral Optoacoustic Tomography for Discovery Diagnosis and Intervention, Insulin resistance and Tauopathy : Insights from Drosophila models and human brain samples, Comprehensive Lifestyle Intervention Project (CLIP), Novel Imaging of the heart for new structural and metabolic diagnosis, Hyper-emotionality after neurodegenerative loss of inhibition of the amygdala, Novel therapeutic approaches to improve gastrointestinal wound healing, Glioblastoma Subtype Avatar models for Target Discovery and Biology, Mitochondrial methylation and its role in health and disease, Age-dependent Regulation of Dendritic Cell Development and Function, Multicellular regulation of insulin secretion from pancreatic islets, Enlightening synaptic architecture: nanoscale segregation of glutamate receptor subtypes, Aging-related changes in brain activation and deactivation during cognition: novel insights into the physiology of the human mind from simultaneous PET-fMRI imaging, Liaison in Scientific Training for European auditory Neuroscience, International Network for Training on Risks of vascular Intimal Calcification And roads to Regression of cardiovascular diseasE, SMALL MOLECULES TO TREAT METABOLIC SYNDROME, Glaucoma – Advanced, LAbel-free High resolution Automated OCT Diagnostics, Biomaterials and Additive Manufacturing: Osteochondral Scaffold innovation applied to osteoarthritis, mitoFOIE GRAS: Non-invasive Profiling of Mitochondrial Function in Non-Alcoholic Fatty Liver Disease, Towards Early Molecular Diagnostics of Schizophrenia, Bioactive compounds from Olea europaea: investigation and application in food, cosmetic and pharmaceutical industry, Microelements in Life Expectancy and Aging, A hands-free remote monitoring solution for continuous and accurate medical grade assessment of heart health, A uniQue platform enabling faster development of treatments for Rare Diseases, Rapid Magnetic Blood Filtration for the Treatment of Sepsis: a Feasibility Study, An effective, side effect-free topical emollient treatment for atopic dermatitis made from a sustainably procured seaweed extract, A novel drug candidate for the treatment of Eosinophilic Esophagitis - an innovative solution for a significant unmet medical need, Plant conditioner enhancing plants' drought resistance based on proline aminoacid, Multisystem Cell Therapy for Improvement of Urinary Continence, Clinical development and proof of principle testing of new regenerative VEGF-D therapy for cost-effective treatment of refractory anginaA phase II randomized, double-blinded, placebo-controlled study, The artificial pancreas in children aged 1 to 7 years with type 1 diabetes, SIMVASTATIN AND RIFAXIMIN AS NEW THERAPY FOR PATIENTS WITH DECOMPENSATED CIRRHOSIS, REgenerative therapy of intervertebral disc: a double blind phase 2b trial of intradiscal injection of mesenchymal stromal cells in degenerative disc disease of the lomber SPINE unresponsive to conventional therapy, Clinical study in Parkinson's disease with two unique goals: 1) Proof-of-concept of CDNF protein for disease modification; 2) Validation of clinically tested device for intracerebral drug delivery, Fast track development of a Zika vaccine based on measles vector, A multicenter phase IIb study using HLA-unmatched allogeneic placenta-derived stromal cells (PLX-PAD) for the treatment of severe critical limb ischemia accompanied by mechanistic studies, Towards evidence-based tailored implementation strategies for eHealth, Development of DIALIVE, a novel Liver Dialysis Device for the treatment of patients with Acute on Chronic Liver Failure (ACLF), A Systems medicine approach to chronic inflammatory disease, SPIDIA for Personalized Medicine - Standardisation of generic Pre-analytical procedures for In-vitro DIAgnostics for Personalized Medicine, Development of a Next-Generation, Dual-Target Rabies/Flavivirus Infectious DNA (iDNA) Vaccine, Integrated Tissue Slice Culture and NMR Metabolomics – A Novel Approach Towards SystemicUnderstanding of Liver Function And Disease, Overcoming the Limits of Diffraction with Superresolution Lighting on a Chip, FORMAT: a novel medium FOr Revolutionizing stem cell MAnufacturing Technologies, Cerebral organoids: human mini brains in a dish open up new possibilities for drug development in neurodegenerative and developmental diseases, Expanding and extending gene therapy of monogenic diseases of the haematopoietic system, Transposable elements, their controllers and the genesis of human-specific transcriptional networks, Cerebral Organoids: Using stem cell derived 3D cultures to understand human brain development and neurological disorders, Beta-cell inflammation and dysfunction induced by bacterial translocation. Effective combinational treatment of chronic pain in individual patients, by an innovative quantitative systems pharmacology pain relief approach. diabetes 1 research news is characterized by. Inflammatory resolution and remodelling of the adipose extracellular matrix: key determinants of a metabolically healthy phenotype? A Non-Invasive GLUCOse MONitoring device for diabetics based on Stimulated Raman Spectroscopy in a quick, cheap and painless method. Disposable nitric oxide POC (point-of-care) test for home care easy management of asthma in chronic patients. Two genetic technologies capable of making heritable changes to the human genome have revived interest in, and in some quarters a very familiar panic concerning, so-called germline interventions. The genetic basis for glial differentiation in the developing zebrafish retina. Diagnostics device for rapid testing of prostate cancer at Point-of-care, Seeing Citrulline: A Molecular Toolbox for Peptidyl Arginine Deiminases, European Proteomics Infrastructure Consortium providing Access, Developing healthy crops for EU: T3SS-Recognition EXploration (T-REX) for plant immunity against bacteria, SIGNALING PROPENSITY IN THE MICROENVIRONMENT OF B CELL CHRONIC LYMPHOCYTIC LEUKEMIA, BETTER TREATMENTS FOR BREATHLESSNESS IN PALLIATIVE AND END OF LIFE CARE, SCale Up an integrated care package for diaBetes and hYpertension for vulnerable people in Cambodia, Slovenia and Belgium, ERA-NET to support the Joint Programming in Neurodegenerative Diseases strategic plan (JPND), a user-friendly procedure that analyses genomic, clinical and demographic data to generate a personalized report with statistical analysis on the efficacy of antidepressants and their side effects, Me-Check - Screening of the dry eye syndrome, On the Origin of Complex Dynamics in Multi-strain Models: Insights for Public Health Intervention Measures, Early conditions, delayed adult effects and morbidity, disability and mortality in modern human populations, Remote Assessment of Disease and Relapse – Alzheimer’s Disease, Smart Autonomous Multi Modal Sensors for Vital Signs Monitoring, CeLac and European consortium for a personalized medicine approach to Gastric Cancer, EURopean wide Innovative Procurement of Health Innovation, Citizen-centred EU-EHR exchange for personalised health, Investigating Mechanisms and Models Predictive of Accessibility of Therapeutics (IM2PACT) Into The Brain, ADvanced nanocomposite MAterIals fOr in situ treatment and ultRAsound-mediated management of osteoarthritis, EVPRO - Development of Extracellular Vesicles loaded hydrogel coatings with immunomodulatory activity for Promoted Regenerative Osseointegration of revision endoprosthesis, Screening of Gastric Cancer via Breath volatile organic compounds by Hybrid Sensing Approach, Behaviour Phenotyping using Inertial Sensors, The evolutionary genetics of transposable element invasions, Chromosome Replication Visualised by Cryo-EM, Super-sensitive detection of Alzheimer’s disease biomarkers in plasma by an innovative droplet split-and-stack approach, NEw Clinical Endpoints in primary Sjögren’s Syndrome: an Interventional Trial based on stratifYing patients, European Health Data and Evidence Network, Preclinical Human In Vitro Drug Immune Response Analysis Platform. Development of a more effective and safer therapeutic antibody for cancer treatment with a dual mechanism of action to eliminate CSCs and reactivate the tumour’s immune system. AlzheimersInAction: A multi-disciplinary approach to determine the cellular and molecular mechanisms underlying the inflammatory response to amyloid-β in Alzheimer’s disease. An Embolic Protection Device for stroke prevention during heart valve replacement. ProbeFix: an Innovative MedTech Solution to improve the use of ultrasound for better Cardiac diagnosis in the EU, Disruptive imaging technology for accurate and painless breast cancer diagnosis. Elucidating the molecular mechanisms of age-related muscle loss to inform Artificial Intelligence-based discovery of novel peptide therapeutics for sarcopenia. Bioinformatics platform for profiling of health: allowing early and accurate detection of multiple diseases simultaneously, Toilet IoT sensor for medical monitoring and wellness tool, Development of an innovative Airway-on-Chip microbiome cell culture model to investigate host-microbiome interactions at the airway epithelial surface, How dopamine affects social and motor ability - from the human brain to the honey bee, What is Tuberculosis? The page lists 2553 projects related to the topic "disease". NLR-ID diversity, mechanism and functionality upon transfer between species, Unravellling the biological determinants of space use patterns in animals, PReterm Enteroids to determine the Mechanism of Necrotising EnteroColitis, Single-molecule visualisation of eukaryotic DNA replication termination to uncover novel mechanisms of replication stress, Understanding the initiation virulence gene expression in African trypanosomes, Neuro-metabolic, structural and functional hallmarks of Lysosomal Storage Diseases. A National Plan that primar- ily targets HABs and their toxins in marine and estuarine waters has been developed, Harmful Algal Research and Response: A National Environ- mental Science Strategy 2005-2015, (HARNESS 2005), but an analogous plan for freshwater HABs has not been developed. Developing Geroprotectors to Prevent Polymorbidity, HD-DittoGraph: a digital human Embryonic Stem Cell platform for Huntington's repeats, A Functional, Mature In vivo Human Ventricular Muscle Patch for Cardiomyopathy, Endoplasmic reticulum structure and synaptic function in Drosophila, Learning and PREdiction based on the PREnatal CONnectome FInGerprint, The unseen adaptation of a non-native: A unique spatiotemporal study of infection dynamics and immunogenetics at a bioinvasion front, SICK OF NOISE - Effects of noise pollution on marine invertebrate health and species interactions, Ultrafast photonics for the detection and recognition of toxic spine-structures of amyloid aggregates linked to neurodegenerative disease, Control of disease tolerance to infection by Biliverdin Reductase A, Cross-talk between skeletal muscle and pancreatic islets: impact of exosomes, Systems Medicine of Metabolic-Signaling Networks: A New Concept for Breast Cancer Patient Stratification, The Comparison of High-Dose Heamodiafiltration (HDF) versus Haemodialyse, Optimizing response to Li treatment through personalized evaluation of individuals with bipolar I disorder: the R-LiNK initiative, Comparing effectiveness of self-management interventions in 4 high priority chronic diseases in Europe, Advancing a Precision Medicine Paradigm in metastatic Colorectal Cancer: Systems based patient stratification solutions, Testing the value of a novel strategic approach and its cost efficacy to improve the poor outcomes in Cardiogenic Shock, Personalised Treatment For Cystic Fibrosis Patients With Ultra-rare CFTR Mutations (and beyond). Comorbidity and Synapse Biology in Clinically Overlapping Psychiatric Disorders, Comorbid Conditions of Attention deficit / hyperactivity disorder. Capturing and quantitative analysis of multi-scale multi-channel diagnostic data. Molecular mechanisms of arenavirus cell entry and antibody-mediated neutralization, Margination of Microcapsules in Small Arteries, Development of pyrrolizidine alkaloid detection methods for the assessment of food contamination and impact on human and animal health, Nanoarrays: Self-assembled Hotspots for Enhanced Analyte Detection, Investigating Ror2-dependent non-canonical Wnt signaling in bone remodeling, Regeneration and zonation by ZEB2 of Liver Endothelium, Bio-sustainable production of natural medicines from Vitex, Genetic correction of glycogen debranching enzyme deficiency in Glycogen Storage disease III: a proof of concept study, Competition between the enteric pathogen Clostridium difficile and the commensal members of the gut microbiota for mucosal sugars, Development of Palladium-Labile Prodrugs for Bioorthogonally-Activated Chemotherapy, Chemical Tools to Probe the Role of Bromodomains in the Parasite Trypanosoma cruzi, A tissue-on-a-chip platform for systems-level studies of ALS pathology and drug screening, Mass Spectrometry-Based Chemoproteomic Profiling of Nav1.7, a Voltage-Gated Sodium Channel, Molecular mechanisms underlying synaptic maintenance and rejuvenation, Investigating the LRRK2-melanin connection through phosphoproteomics of isogenic melanoma cells, Ostreid herpesvirus 1: Genetic selection of Resistant strains and environmental interaction in the Atlantic coast of Spain (Galicia), Discovering the signalling pathways and physiology of active rhomboid proteases in the brain, Regulation and consequences of LRRK2 phosphorylation,a path to Parkinson’s disease therapy and diagnostics, Molecular epidemiology of Bacillus anthracis: novel data and techniques for local surveillance in Tanzania. Women’s Plague Writing in Early Modern England, Fully Integrated Technology based on quantitative polymerase chain reaction for the diagnosis of Urinal Tract Infection. CaMKII over stimulation in engineered heart tissues (EHTs) made from human induced pluripotent stem cells (hiPSCs): a parameter involved in the immaturity of hiPSC EHTs cardiomyocytes? Novel Target for Treatment of Chronic Inflammatory Diseases, Noninvasive cell specific morphometry in neuroinflammation and degeneration, Cognitive Aging: From Educational Opportunities to Individual Risk Profiles, Development and Commercialisation of an Intelligent Wearable Platforms to Stabilise Hand Tremors in Parkinson’s Disease and Essential Tremor, Oral bacteria as determinants for respiratory health, Navigation of a mind-space. LeukoPredict: an in vitro system predicting and monitoring the therapeutic response of patients in the cure of Chronic Myeloid Leukemia (CML). Confined, Optically Enhanced, X-ray Imaging Source for Tomography, Role of intestinal fungal communities in arthritic pathology, Metabolic regulation of mitochondrial morphology, Investigating the regulation of iron homeostasis by erythroferrone and therapeutic applications, Microglia action towards neuronal circuit formation and function in health and disease, The role of the virome in shaping the gut ecosystem during the first year of life, Research Infrastructures for the control of vector-borne diseases. Medical device combining viscosupplementation with pharmacological active molecule to regenerate cartilage in degenerative or traumatic osteoarthritis. Micro/Nano Robotics for Single Cancer Cells, How to help the hive? Function of DUX4 in skeletal muscle and non-muscle tissues, Tracking the temporal and geographic origins of modern domestic horses, Enhancing Engulfment of Apoptotic cells: basic biology to Therapy, From marine molecules to eco-friendly tools for agriculture, Progeria models to study endothelial cell ageing: implications for organ regeneration and fibrosis, Advancing the non-invasive assessment of brain communication in neurological disease, Building biological computers from bacterial populations. Epigenetic regulation of cardiac regeneration after injury. Cyclic nucleotide signalling in the human pathogen Listeria monocytogenes, Characterization of islet-specific CD8 T cells in the honeymoon of type 1 diabetes, The Application of Advanced Raman Spectroscopies to the Quantitative Analysis of Industrial Chromatography Columns, ENgineering DYnamic ViscoElasticity to study cell response, Eat me microglia: lipid scrambling as a signal for synaptic pruning. ALTERNATIVE SPLICING NETWORKS IN PANCREATIC BETA CELLS, Roles of spastic paraplegia proteins in organisation of axonal endoplasmic reticulum, Ex vivo Re-vascularization in Porcine Liver Bioengineering - A Critical First Step Towards Effective Transplantation of Bioengineered Livers, Rewiring Brain Units - bridging the gap of neuronal communication by means of intelligent hybrid systems, Micro-RNAs of neutrophils in renal ANCA-associated vasculitis, Selective vulnerability of neuronal degeneration in Parkinson’s disease: the load of routine behaviour, Identification and characterization of new cytosolic ligands of Sortilin, Characterising the spatial organisation and regulation of the Wnt receptor complex in stem cells and cancer. Interdisciplinary training network on the purinergic P2X7 receptor to control neuroinflammation and hyperexcitability in brain diseases. Hybrid optical and optoacoustic endoscope for esophageal tracking. Advancing cancer detection through metabolism-based diagnostics, QSEIF: The new pathogen, DNA and immunological testing platform, Lakhesys: building the machine to make the medicines of tomorrow, An e-Health expert system for diagnosis and treatment of diabetics to reduce the risk of skin breakdown and co-existing foot diseases. In seventh chapter, endophytic fungi from ten plants growing in the speci ed Himalayan regions have been studied for their phylogenetic a nities and bioactive potential. IPUD – An Implantable Peritoneal Ultrafiltration Device that actively and continuously prevents fluid overload in diuretic resistant heart failure patients. Of age-related muscle loss to inform Artificial Intelligence-based discovery of immune Suppression a study for the treatment retinal... Inflammatory systems in hypertension cross-linking agent: Unlocking a new Technological instrument for research and markets! 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